become very drowsy with slowed breathing.You or someone close to you should call 911 or get emergency medical help right away if you: It is important that you tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose. when your next naltrexone injection is due.after you have gone through detoxification.You may also be more sensitive to the effects of lower amounts of opioids: If you have used opioid street drugs or opioid-containing medicines in the past, using opioids in amounts that you used before treatment can lead to overdose and death. After you receive a dose of the extended-release injection form of this medication, its blocking effect slowly decreases and completely goes away over time.This can lead to serious injury, coma, or death. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of this medication. Naltrexone blocks the effects of opioid drugs.You can accidentally overdose in two ways. Naltrexone can cause serious side effects, including: Naltrexone hydrochloride should not be used in children and adolescents under 18 years. You should stop drinking alcohol or using opioids before starting naltrexone. To prevent relapse to opioid dependence, after opioid detoxification. for the blockade of the effects of exogenously administered opioids.Naltrexone is a prescription medication that is used: In 2006, the FDA also approved Vivitrol, the extended-release intramuscular injection form of naltrexone. Naltrexone tablets were first approved by the US Food and Drug Administration (FDA) in 1984. The branded versions of naltrexone tablets (Revia, Depade) have been discontinued, but generic versions are available. Naltrexone comes as an extended-release intramuscular injection ( Vivitrol) and as oral tablets.

Naltrexone also modifies how the hypothalamus, pituitary gland and adrenal gland (hypothalamic-pituitary-adrenal axis, HPA axis) interact to suppress the amount of alcohol consumed. It blocks the effects of alcohol and opioid medications, preventing the intoxication these substances cause. Naltrexone belongs to a class of drugs known as opioid antagonists and works by blocking the mu opioid receptor. It helps you stop using these substances and remain off them. Naltrexone is a prescription medication used to treat alcohol use disorder and opioid use disorder. Medically reviewed by Philip Thornton, DipPharm. Generic name: naltrexone, naltrexone hydrochlorideĭosage form: extended-release intramuscular injection (powder for suspension), oral tabletĭrug classes: Antidotes, Drugs used in alcohol dependence

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